Acid-base balance

Normal values

  • Normal range of arterial blood pH and the importance of maintenance of this range
  • Henderson-Hasselbach equation for bicarbonate and CO2 equilibrium
  • The anion gap - components and calculation

Metabolic disturbance

  • The typical ABG features of metabolic + respiratory alkalosis and acidosis
  • An understanding of the primary systemic compensations which occur in each type
  • Metabolic acidosis differentials
  • Urinary acidification (bicarbonate reabsorption + acid formation + handling of ammonia)
  • The kidneys as net renal excretors of acid
  • Factors influencing renal secretion and excretion of hydrogen