Functional anatomy

Gross anatomical location - Thyroid
Site of production of T3 and T4 (details of cellular manufacture not needed)

Transport of thyroid hormones

Normal values of TSH and T4 hormone in health

TSH: 0.4-4.5 milliunits per litre
FT4 (Free T4): 9-25 picomoles per litre
FT3 (Free T3): 3.5-7.8 picomoles per litre

Importance of binding proteins in transport and concept of ‘free’ hormone
Peripheral metabolism of T4 to T3

Physiological effects

Cardiac output, and calorigenic effect, as type examples

Effects of disordered function

Physiological basis of hypo- and hyper- thyroidism: see

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