catecholamines

Secreted in adrenal medulla

  • sympathetic stimulation via sympathetic preganglionic neurons → secretion of adrenaline + noradrenaline
    • dual control of sympathetic stimulation: direct nervous stimulation AND effects of adrenaline/noradrenaline

breakdown

  • intracellularly: COMT
  • extracellularly: MAO in mitochondria