calcitonin
made from procalcitonin!!!
PTH has much stronger effect on serum calcium.
| Net effect: | ↓ serum calcium, basically the opposite of PTH |
|---|---|
| Secreted from | parafollicular cells (C cells) of thyroid |
| Stimulus | high serum calcium (via CaSR) |
| Inhibition | |
| Acts on (action) | see below |
| Action (function) | see below |
effects
| Site | Action |
|---|---|
| Bone | ↓ osteoclast activity ↓ formation of new osteoclasts |
| Kidney | ↑ excretion of Ca (and phosphate) ↑ production of calcitriol in kidney |