ANP

Atrial natriuretic peptide

Net effect: Delays decompensation of heart function in hypervolaemia (as in congestive heart failure)
Secreted from Atrial walls
Stimulus Atrial stretch - hypervolaemia
Inhibition
Site of action Distal tubule
via cGMP messaging
Action (function) - ↑ Na and water excretion (or ↓NaCl reabsorption) in kidneys
- ↓ renin secretion
- ↓ ADH

#renal #endocrine

Guyton