Vasopressin as a vasopressor
Strictly speaking this is purely from an ICU interest POV. But I think it's relevant...
Supported by Surviving Sepsis Guidelines as an option for refractory hypotension but not recommended as first line vasopressor (Dellinger et al, 2012)
| Uses: | oesophageal varices, neurogenic diabetes insipidus |
|---|---|
| Mechanism of action | ↑ reabsorption of water, smooth muscle contraction → vasoconstriction |
| Dose | |
| Pharmacokinetics | Absorption IV, IM, SC Distribution Metabolism liver, kidney. Elimination Urine. t½ 10-20 min |
| Time course of action | Fast onset Effect maintained 2-6h |
| Adverse effects | Uterine contraction Digital ischaemia |
related topics
Other Inotropes are available.
Should be aware of its effect as a hormone too.