Sodium nitroprusside
| Uses: | |
|---|---|
| Mechanism of action | donor of NO - increased cGMP in vascular smooth muscle |
| Dose | |
| Pharmacokinetics | Absorption: 0% PO bioavailability Distribution Metabolism either decomposition, or binding with Hb Elimination onset within seconds; t 1/2 of 2 minutes |
| Time course of action | |
| Adverse effects | |
| Contraindications | impaired cerebral circulation Lever's optic atrophy (what) B12 deficiency |