atropine
| Uses: | Bradycardia â effect: â SAN/AVN conduction Topical: cycloplegia, uveitis Also causes bronchodilation |
|---|---|
| Mechanism of action | Antimuscarinic - antagonises ACh at postganglionic nerve endings |
| Presentation | 100mcg/ml, 300mcg/ml, or 600mcg/ml concentrations available Prefilled syringes: 3mg in 10ml = 300mcg/ml |
| Dose | ALS: 500 mcg up to total of 3mg Anaesthetic context: 0.6-1.2mg = 2-4ml |
| Pharmacokinetics | Absorption Distribution Metabolism Elimination t½ 2-5h |
| Time course of action | |
| Adverse effects | Anticholinergic effects: urinary retention, â intestinal/gastric motility, dries up secretions |
(see also glyco I guess)
#pharmacology #cardiac-physiology
see that novpod