Acute aortic syndromes

Aortic dissection

classification

  • Stanford Type A vs B
    • A: ascending aorta +/- arch
    • B: distal to origin of L subclavian artery
  • DeBakey Type 1/2/3
    • 1: entire aorta
    • 2: ascending aorta and/or the arch of the aorta
    • 3: only the descending aorta

progression

tear of intima
Etiology/Risk factors - Inherited disease: connective tissue disorders - EDS, Marfan's
- ↓ resistance across aortic wall: pregnancy, ↑ age
- Aortic wall stress: hypertension, cocaine misuse, arteritis, infection (syphilis)
Clinical presentation 80-90% present with pain - anterior chest, posterior chest, less commonly abdo
Others: focal neurology - TLOC, paraplegia (occlusion of spinal arteries), stroke and stroke-like symptoms; acute heart failure
- widened pulse pressure
- BP discrepancies - 20% of patients
risk stratification ADD-RS
Pathogenesis arterosclerotic ulcer → intima tear; or disruption of vasa vasorum; de novo intimal tear → blood into false lumen
Diagnostic investigations ECG:
Gold standard: CT aorta
Management Decide if you need:
Impending bleeding doom
  • Escalate early (to whichever specialty should be stopping the bleed)
  • Right place - resus, and on to theatre? IR?
    Vasc access and bloods:
  • 2x large bore cannula
  • Crossmatch, FBC, coag screen, VBG, LFT
    Haemostatic rescuscitation:
  • TXA (not for UGIB/peptic ulcer disease)
  • Correct coagulopathy
  • Anticoagulant reversal
    Optimise clotting: keep warm, aim iCa >1.1 (10ml 10% Ca gluconate PRN)

Buy time to surgical intervention if appropriate
Analgesia!
Beta blockers then vasodilators (avoid reflex tachycardia)
Type A typically gets surgical repair; Type B typically supportive care

Ruptured aortic aneurysms

AAA screening

AAA definition: permanent pathological dilation of the abdominal aorta with a diameter over 1.5 times the expected anteroposterior diameter of that segment

  • diagnostic threshold = >3.0cm
  • Men >65 get a one off abdo USS
    • No aneurysm found (less than 3.0 cm) — no further scans are required. 
    • Small AAA (3.0 cm to 4.4 cm) — the person is placed under surveillance and a repeat scan offered in 12 months. 
    • Medium AAA (4.5 cm to 5.4 cm) — the person is placed under surveillance and a repeat scan offered in 3 months. 
    • Large AAA (5.5 cm or larger) — the person is referred to a vascular surgeon.