asthma

had to bite the bullet and create this gargantuan document sometime. oh well.
Asthma in children
Chronic management of asthma

acute exacerbation

risk stratification

Adults Children
Near-fatal Raised PaCO2 and/or requiring mechanical ventilation with ↑ inflation pressures
Life-threatening symptoms: cyanosis, drowsy, exhaustion, poor respiratory effort, confusion (may be a sign of hypoxia)
signs: oxygen saturation on air less than 92%; hypotension; PEF less than 33% best or predicted; and/or 'silent chest'.
PaCO2 normal (4.5-6.0)
same as adults
Acute severe inability to complete sentences in one breath



oxygen saturation on air less than 92%;

PEF 33–50% best or predicted


pulse rate more than 110 beats per minute; and




respiratory rate more than 25 breaths per minute
too breathless to talk or feed; use of accessory neck muscles
oxygen saturation on air less than 92%

PEF 33–50% best or predicted
> HR >140 - age 2–5 years
> HR >125 - age >5 years

> RR >40 - age 2–5 years
> RR >30 - age >5 years
Moderate talking in sentences; prefers sitting to lying; not agitated;
no accessory muscle use;
oxygen saturation on air 92% or more;
PEF more than 50% best or predicted, and
no features of acute severe asthma.
talking in sentences
oxygen saturation on air 92% or more
PEF more than 50% best or predicted

> HR <140 - age 2–5 years
> HR <125 - age >5 years

> RR <40 - age 2–5 years
> RR <30 - age >5 years.

discharge guidance

  • If there are signs of a moderate exacerbation, assess whether the person can be managed at home, if:
    • There is a good response to initial treatment and symptoms have improved.
    • PEF is improving to more than 60–80% of best or predicted.
    • Oxygen saturation on air is more than 94%.
    • The person is able to manage at home with appropriate support.

Corticosteroid duration

Continue oral prednisolone until recovery. Dose tapering is not needed if prednisolone is prescribed for less than 2 weeks. Advise not to stop ICS while taking oral prednisolone treatment.

  • In adults and children aged 16 years and over continue for a minimum of 5 days or until recovery if longer.
  • In children aged 6–15 years, continue for a minimum of 3–5 days or until recovery if longer.
  • In children aged 2–5 years, continue for a minimum of 3–5 days or until recovery if longer.

critical care considerations