Sarcoidosis
| Headline | |
|---|---|
| Etiology | Non-caseating granulomas in affected tissue. Linked with HLA-B8? |
| Epidemiology | |
| Clinical presentation | Ddx: ("Löfgren syndrome") fever, hilar LNA, erythema nodosum. Symmetric arthritis, erythema nodosum facial nerve palsy, splenomegaly, uveitis, sicca... Ddx: lymphoma, TB |
| Pathogenesis | |
| Diagnostic investigations | ECG, CXR, lung function tests, CT chest, calcium (↑), serial ACE. Histology is dxc. |
| Management | Complications: hypercalcaemia steroids if symptomatic; inhaled steroids to control cough, pulmonary rehab 66% remission without treatment |
| Prevention |