molar pregnancy
| Headline | |
|---|---|
| Etiology | 1 sperm fertilise empty ovum or 2 sperm fertilise same ovum. RF: extremes of maternal age, previous hx, ethnicity (Asian). Malignant potential = gestational trophoblastic neoplasm. |
| Epidemiology | |
| Clinical presentation | Hyperemesis gravidarum, PV bleed, uterus large for dates |
| Pathogenesis | |
| Diagnostic investigations | b-HCG: ↑↑ TVUS: "snowstorm" appearance |
| Management | Complications: choriocarcinoma. ERPC - Serial b-HCGs - Gestational trophoblastic neoplasm: methotrexate. Mets: lung, bladder/bowel, brain |
| Prevention |