subarachnoid haemorrhage
| the notorious "thunderclap" | |
|---|---|
| Etiology | 85% aneurysmal (van Gijn and Rinkel 2001), with highest risk of rebleed in first few days |
| Epidemiology | F>M 1.6:1. Peak age: 50-55. Risk factors: age, hypertension, smoking, ADPKD |
| Clinical presentation | maximal onset within seconds to minutes |
| Pathogenesis | |
| Diagnostic investigations | CT within 6h - less useful after that LP - xanthochromia CT angiogram after 2/52 Ddx: reversible cerebral vasoconstriction syndrome - usually accompanied by trigger (Cittadini and Matharu 2009) |
| Management | A/B: does this patient need I+V (airway protection) C: Nimodipine - prevent vasospasm; BP control; Anticoagulant reversal if necessary D: Neurosurgical referral for clipping/coiling, ICP management Screening: only if >1 first-degree relative affected - only via specialty services to offer appropriate counselling |
ottawa SAH rule: investigate further if any of the 6 rules are met
- neck pain/stiffness
- onset during exertion
- peak intensity immediately
-
= 40 years old
- witnessed LOC
- limited neck flexion on examination
recent relevant research: SHED-CT
sources/links
Relevant studies: SHED https://emj.bmj.com/content/41/12/719
http://www.ncbi.nlm.nih.gov/pubmed/11157554
Cittadini E, Matharu MS. Symptomatic trigeminal autonomic cephalalgias. Neurologist 2009;15:305-312.
https://www.bmj.com/content/389/bmj-2024-083247/infographic
https://www.nice.org.uk/guidance/NG228