Rotavirus
| the rotavirus vaccine prevents 97% of severe rotavirus diarrhoea in low-mortality countries in the first year of life! | |
|---|---|
| Etiology | encapsulated double-stranded RNA virus |
| Epidemiology | resistance via genetic reassortment peaks during cold months |
| Clinical presentation | |
| Pathogenesis | infects and destroys mature enterocytes - mediated by nonstructural protein 4 (NSP4) |
| Diagnostic investigations | |
| Management |
prevention
routine vaccination at 2 and 3 months - live attenuated