Herpes simplex

Simplex and varicella zoster are the type examples of herpesviruses which form required knowledge.

You should, however, be aware of the fact that the herpes family encompasses cytomegalovirus and Epstein-Barr virus, although the specific features of these two viruses are not **required.

Herpes simplex

 Epidemiology: mode of transmission; problems encountered in the immunocompromised
 Clinical features of infection: differentiation of clinical features of HSV-1 and 2 → Herpesvirus infections
 Basis of diagnosis: the role of imaging in herpes encephalitis
 Treatment options, in particular the management of encephalitis

Varicella zoster

 Epidemiology: patterns of disease; incubation; dormancy of virus
 Clinical features of infection: chronology of skin changes; VZV pneumonia; shingles
 Basis of diagnosis: appreciation of the fact that diagnosis is essentially clinical
 Treatment: role of acyclovir; role of immune globulin in pregnancy