Hepatitis A

No chronic hepatitis or carrier state!
Etiology 27nm non-enveloped RNA virys
Epidemiology Faecal oral spread
Clinical presentation: 2/7 - 2/52: flu-like prodrome
1-3 weeks: icteric period
Investigations Anti-HAV IgM = diagnostic
Past infection: anti-HA
Management Unvaccinated + recent exposure: vaccine +/- Normal immunoglobulin

otherwise supportive as for any liver failure

public health

  • vaccination for travellers to high-risk areas (unless age <1 year)
  • You get normal immunoglobulin if you are a close contact of confirmed cases AND:
    • chronic liver disease
    • HIV
    • immunosuppressed, OR
    • age >50

#HPB #pathology #virology

source

BMJ best practice

https://bestpractice.bmj.com/topics/en-gb/126/
which countries? https://travelhealthpro.org.uk/countries