sequelae of varicella exposure in pregnancy

`` ObC3

higher risk pregnant patients:

  • Pregnancy approaching term.
  • Previous obstetric complications or risk factors.
  • Smoking.
  • Chronic lung disease.
  • Social risk factors.
  • Close monitoring in the community is not possible.

potential sequelae for infant

1st 20 weeks: congenital varicella

30% mortality
Clinical presentation:

  • segmental skin loss
    • depressed and pigmented in a dermatomal distribution
  • limb hypoplasia
  • ocular defects:
    • cataracts, chorioretinitis
    • Horner syndrome
    • microphthalmos
    • nystagmus
  • ↓ birth weight
  • CNS abnormalities: seizures, microcephaly

2nd/3rd trimesters: neonatal herpes zoster

  • vesicular eruptions
  • complications of disseminated disaese

7 days before to 7 days after delivery

#gynae-obstetrics

Obs gynae MRCEM syllabus

EOE Neonatal ODN guidelines: https://eoeneonatalpccsicnetwork.nhs.uk/neonatal/downloads/varicella-guideline/