Mpox
| Headline | |
|---|---|
| Etiology | Orthopoxvirus. Clade II responsible for worldwide outbreak (previously found in West Africa). |
| Epidemiology | Endemic to DRC, but UK outbreak in 2022. Transmission: zoonotic, or human-human via contact, respiratory secretions |
| Clinical presentation | Prodrome (1-4 days before rash): flu-like symptoms Rash: blisters on genitals, hands, feet, chest, face or mouth, lasting 2-4 weeks Complications: Pneumonia, encephalitis, keratitis/corneal ulceration |
| Pathogenesis | |
| Diagnostic investigations | PCR from skin lesion |
| Management | Inpatients will need negative pressure isolation Isolate until last skin lesion heals Supportive Notifiable disease. |
| Prevention | Vaccine available for high-risk people. |