Malaria treatment

resuscitation as normal

A:
B: w

severe disease

  • Parenteral: artesunate
  • PO: artemether/lumefantrine, or atovaquone/proguanil (Malarone), or quinine + doxycycline/clindamycin

in pregnancy

  • Parenteral: artesunate
  • PO: quinine + clindamycin

uncomplicated disease

  • chloroquine/hydroxychloroquine
  • If resistant region: artemether/lumefantrine or Malarone

prophylaxis

mefloquine (18d before – 4/52 after; avoid w hx/Fhx of psychosis, epilepsy; may be pregnant within 3/12 of last dose), doxy (1d before-4/52 after), Malarone atovaquone+proguanil (OD 1d before - 7d after)