HIV opportunistic infections

The best prevention is good adherence to ART!

Pathogen Criteria for prophylaxis
pneumocystis jirovecii pneumonia prophylaxis if CD4<200: co-trimoxazole, dapsone or atovaquone
Toxoplasmosis IgG testing for latent infection
prophylaxis if CD4<100: co-trimoxazole, dapsone
Tuberculosis Testing for latent infection
Mycobacterium prophylaxis if CD4<50: azithromycin, clarithromycin
CMV Aim to maintain CD4 >100
Cryptococcal meningitis prophylaxis if CD4 <100 with positive screening cryptococcal antigen
if screening not available, then prophylaxis if CD4 <100: fluconazole
Candida No routine prophylaxis recommended
Coccidiodomycosis - avoid exposure to disturbed native soil (e.g., at building excavation sites) and to remain inside during dust storms
- serological testing
- screening if asymptomatic, living in endemic areas and CD4<250