Vertigo

differentials (many)

  • Benign paroxysmal positional vertigo - Hallpike’s test diagnostic
  • Meniere's disease
  • labyrinthitis: ± URTI prodrome
  • posterior stroke: other focal neurology e.g. Acute ataxia
  • Otitis media
  • acoustic neuroma: slow onset deafness (rarely causes vertigo)
  • trauma, foreign body
  • vestibular neuronitis: post-infectious, hearing is normal
  • migraine
  • drug-induced: gentamicin, co-trimoxazole, diuretics, metronidazole

red flags for central cause

  • new onset headache, Head injury
  • other focal neurology - cranial nerve palsy, etc.
  • ataxia

more likely to be peripheral if:

  • hearing loss (although stroke can cause hearing loss also)
  • N+V

HiNTS exam

Part Posterior stroke will give...
Head impulse Normal/negative head impulse test
Nystagmus Rotatory/vertical nystagmus; direction-changing horizontal nystagmus
Test of skew Skew deviation/positive vertical skew test

pharm management

  • Betahistine - H1 receptor agonist, H3 antagonist → ↑ cochlear blood flow ...? inhibition spike generation of neurons in vestibular nuclei