myocardial infarction

Headline
Etiology
Epidemiology
Clinical presentation
Pathogenesis
Diagnostic investigations ECG - we all know about ST elevation but what about STEMI equivalents?
Immediate management 300mg loading aspirin ASAP, then:
go to PPCI if:
- presenting within 12h of s/s and PCI can be done in 120 mins, or
- >12h and ongoing myocardial ischaemia/cardiogenic shock
then:
- prasugrel/clopidogrel/ticagrelor + aspirin if not already anticoagulated
- clopidogrel + aspirin if already anticoagulated

if presenting within 12h of s/s and PCI cannot be done in 120 mins, fibrinolysis is indicated
then:
- ticagrelor + aspirin or aspirin +/- clopidogrel if high bleeding risk
- no further fibrinolysis, any further intervention = PCI

cognitive priming - ECGs

Evolving anterior MI
ECG-Anterior-STEMI-evolving.jpg

Inferior MI
inferior-MI-LITFL.png

secondary prevention

  • ACE inhibitor - indefinitely
  • DAPT - up to 12 months
  • beta blocker - indefinitely if ↓ LV function; else, at least 12m
  • statin
  • MRA - if ↓LVEF, start 3-14d after MI

weird and wonderful

fun fact, MI can occur with Anaphylaxis = "Kounis syndrome" - caused by coronary spasm, displacement of atheromatous plaques because of coronary spasm or stent thrombus
https://www.rcemlearning.co.uk/modules/stinging-the-heart/