Hypertensive emergency
- Some define it as BP >180/110???
- British and Irish Hypertension Society 2023: elevated BP, which when sustained over the next few hours may lead to progressive life-threatening end organ damage
- End-organ damage makes it an emergency - without this, it is simply 'urgency'
- MI, acute heart failure
- intracranial haemorrhage or hypertensive encephalopathy
- eclampsia
- has their own methods for lowering BP:
- Aim ↓ 20-25% in first 2 hours
if treatment is truly indicated...
For hypertensive emergencies, the aim is to reduce Mean Arterial Pressure (MAP*) by up to 25% in the first hour of treatment
choice of agents
- sodium nitroprusside
- advantages: rapid on and offset, titratable
- labetalol - alpha and beta blockade = vascular smooth muscle dilatation
- advantages: no reflex tachycardia
- predictable and titratable
- nitrates - GTN. ↓ preload
- advantages: coronary vasodilator
- useful if patient is bradycardic tho
- nicardipine
- advantages: considered safe in pregnancy
- disadvantages: -ve inotrope
- hydralazine
- disadvantages: reflex tachycardia; avoid in cerebral disease
related topics
sources/links
Miller et al 2024 BMJ https://www.bmj.com/content/386/bmj-2023-077205
Stewart 2023 https://journals.lww.com/co-cardiology/abstract/2023/07000/hypertensive_crisis__diagnosis,_presentation,_and.6.aspx
https://www.rcemlearning.co.uk/foamed/treat-or-hold-decoding-high-blood-pressure-in-the-emergency-room/
https://pmc.ncbi.nlm.nih.gov/articles/PMC5880769/
https://www.rcemlearning.co.uk/reference/hypertensive-emergencies/
https://emcrit.org/emcrit/hypertensive-emergencies/
Adnerson et al 2023 https://pubmed.ncbi.nlm.nih.gov/37252732/
https://www.rcemlearning.co.uk/foamed/aortas/