cardiomyopathies
see HOCM
| Dilated | |
|---|---|
| Etiology | Associations: alcohol, hypertension, HH, pregnancy, thyrotoxicosis, chemotherapy (dauno/doxorubicin), Muscular dystrophy. |
| Epidemiology | |
| Clinical presentation | ↑ HR, ↓ BP, S3 gallop, MR/TR/ pleural effusion, oedema, jaundice, hepatomegaly, ascites |
| Pathogenesis | nuclear hypertrophy, interstitial fibrosis, lymphocytic infiltration |
| Diagnostic investigations | |
| Management | Manage the heart failure |
| Constrictive | |
|---|---|
| Etiology | idiopathic, rheum (amyloid, sarcoid, scleroderma), haemochromatosis. |
| Epidemiology | |
| Clinical presentation | Similar to constrictive pericarditis |
| Pathogenesis | "rubbery, non-compliant” myocardium, bilat hypertrophy; eosinophilic deposition/honeycomb pattern around myocytes |
| Diagnostic investigations | Echo - diastolic dysfunction |
| Management | Manage the heart failure Complications: Pulmonary hypertension, SOB, R ventricle hypertrophy |