Brugada syndrome
diagnosis depends on ECG AND clinical criteria
| can cause Sudden cardiac death "previously described as Sudden Unexplained Nocturnal Death Syndrome" |
|
|---|---|
| Etiology | sodium channelopathy |
| Epidemiology | high incidence in SEA |
| Clinical presentation | ECG changes may be transient/unmasked by other metab stress. Clinical criteria: - documented VF/VT - family history of sudden cardiac death age <45 - coved-type ECG in family members - inducible VT with electrical stimulation - syncope - nocturnal agonal respiration |
| Pathogenesis | |
| Diagnostic investigations | Type 1: Coved ST segment elevation >2mm in >1 of V1-V3 followed by a negative T wave Type 2: >2mm saddleback shaped ST elevation Type 3: type 1 or 2, but <2mm |
| Management | ICD is definitive |
related topics
sources/links
Larkin et al 2024 - https://litfl.com/brugada-syndrome-ecg-library/
Rezaie 2013 - https://www.aliem.com/2013/brugada-syndrome-an-ecg-pattern-you-need-to-know/