acute heart failure

joblist: evidence from mike's presentation re GTN. LR for each. reformat to easier to read format, currently more like DP format. link to NICE guidelines.

clinical presentation

airway/breathing

circulation

  • ↓ cardiac output
  • pulm cap wedge pressure ↑ as patient gets more unwell

disability

  • anything that comes with brain hypoperfusion

exposure

  • hypoperfusion →
    • peripheral vasoconstriction
    • ↑ lactate

etiology: why now?

Think about causes of an acute detioeration in cardiac function
Feel free to sort this into whatever surgical sieve you prefer.

  • cardiomyopathy: ischaemia (big ticket), other cardiomyopathies e.g. takotsubo, myocarditis, alcoholic; autoimmune or congenital; trauma (contusion)
  • volume overload: iatrogenic, renal failure
  • hypovolaemia: dehydration, overdiuresis
  • arrhythmia
  • valve dysfunction including LVOTO
  • drug-related
    • non-adherence to therapies
    • iatrogenic
      • negative inotropy - e.g. beta blockade
      • volume overload
      • cardiotoxic effects of pchemotherapy agents
    • alcohol, cocaine
  • SEPSIZZZZ... endocarditis, myocarditis

management/interventions

  • CPAP/BIPAP
  • invasive ventilation might be needed for haemodynamic instability, or if required for procedures
  • therapeutic drainage? → to buy time to correct the heart failure

afterload reduction

  • GTN
  • inodilators - milrinone or dobutamine
    • milrinone works slowly
  • inopressors - norad, low dose adrenaline (to make use of the +ve inotropic effects)

managing fluid status

  • tricky to say the least......
  • 50% are euvolaemic (source needed)
  • Depends on Right heart failure

treating underlying cause

  • tachyarrhythmia - if AF etc., maybe useful. but sinus tachy might be part of compensation!
  • MI → revascularisation

pitfalls

  • don't start beta blockers in this context - this is for stable chronic heart failure
  • don't rely just on furosemide - plus evidence points to benefit from vasodilation rather than diuresis