Saliva production

innervation

Parasympathetic

  • Originate in salivatory nuclei
  • Parotid glandCN IX via otic ganglion
  • other glands above oral fissure: greater petrosal nerve of facial nerve
    • preganglionic fibres synapse in pterygopalatine ganglion
    • postganglionic fibres join maxillary nerve
  • other glands below oral fissure: chorda tympani of facial nerve
    • preganglionic fibres synapse in submandibular ganglion
    • postganglionic fibres travel directly to glands

sympathetic

  • origin: T1
  • preganglionic fibres synapse in Superior cervical ganglion
  • postganglionic fibres 'hop onto adjacent blood vessels and nerves' lol
Parasym Sympathetic
↑ volume saliva ↑ amylase secretion, ↓ water content

composition

  • parotid - mostly serous
  • submandibular, sublingual - serous and mucus
  • buccal - mucus
    1000ml/day

ions

  • high K, high HCO3

enzymes

  • amylase
  • lipase
  • kallikrein - splits alpha-2 globulin to bradyknin = vasodilation = ↑ blood supply to glands

immune role

  • IgA antibodies
    • lysozyme - bacteriocidal